On April 22, 1954, President Dwight D. Eisenhower nominated Lawrence Quincy Mumford for the post of Librarian of Congress. Mumford was the eleventh person to hold the office and the first trained as a professional librarian.
On April 22, 1861, the U.S. Arsenal at Fayetteville surrendered to a force of state militia troops roughly a month before North Carolina seceded from the Union.
On April 21, 1864, the state salt works in New Hanover County were attacked by Federal forces and about a third of the site was destroyed.
On April 21, 1941, New York City Mayor Fiorello LaGuardia dedicated the Charlotte Douglas International Airport in front of a crowd nearly 10,000 local residents.
On April 20, 1971, the Supreme Court issued its opinion in the Swann v. Charlotte-Mecklenburg Board of Education case, allowing for school desegregation by busing.
On April 20, 1898, the Fries Manufacturing and Power Company transmitted electrical power 13 miles from the generating plant to the Fries-owned Arista textile mill.
On April 19, 1585, Algonquian Indians Wanchese and Manteo set sail aboard the English vessel The Tyger to return to the Roanoke Island region.
